Wong was born in San Francisco, California, the son of Roberta Christine (n??e Leong), a telephone company supervisor, and William D. Wong. He is of Chinese descent. Wong attended Lincoln High School before attending San Francisco State University.

Wong gained attention for his Broadway debut in M. Butterfly opposite John Lithgow. The play won multiple awards, including several for Wong. He is notable as the only actor to be honored with the Tony Award, Drama Desk Award, Outer Critics Circle Award, Clarence Derwent Award, and Theatre World Award for the same role. In addition to his long-running stint on as FBI psychiatrist Dr. George Huang, he has had recurring roles in All American Girl and as a prison priest on Oz , with guest appearances on The X-Files and Sesame Street. On the big screen, he has appeared in The Freshman (1990), the 1991 remake of Father of the Bride and its 1995 sequel, Mystery Date (1991), Jurassic Park (1993), Executive Decision (1996) and Slappy and the Stinkers (1997). He also provided the voice of Captain Shang in Disney's Mulan (1998) and its direct-to-video sequel . He returned to Broadway as Linus in a revival of You're a Good Man Charlie Brown, alongside Anthony Rapp, Roger Bart and Kristin Chenoweth, and the 2004 revival of Stephen Sondheim's Pacific Overtures. In 2008, he starred in the one-man show Herringbone , in which he portrays 11 roles, at the McCarter Theatre at Princeton University. He brought the show to the La Jolla Playhouse in San Diego the following year.

Wong also co-starred in the movie Executive Decision alongside Steven Seagal and Kurt Russel.

Wong, who is openly gay , began a long-term relationship with talent agent Richie Jackson in 1988. In 2000, Wong had twin sons: Boaz Dov, who died 90 minutes after birth, and Jackson Foo Wong. They were born through a surrogate mother, using Wong's sperm and an egg donated by Jackson's sister. In 2003, Wong wrote a memoir about his experiences with surrogacy titled Following Foo: the Electronic Adventures of the Chestnut Man . Wong and Jackson ended their relationship in 2004.

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Year	Film	Role	Notes
1986	''The Karate Kid, Part II''	Boy on Street	as Bradd Wong
1989	''Family Business (film)|Family Business''	Jimmy Chiu, Adam's MIT Prof		-	1990	''The Freshman (1990 film)|The Freshman''	Edward		-	rowspan=2|1991	''Mystery Date''	James Lew		-	''Father of the Bride (1991 film)|Father of the Bride''	Howard Weinstein		-	1992	''The Lounge People''	Billy		-	1993	''Jurassic Park (film)|Jurassic Park''	Henry Wu		-	rowspan=2|1994	''The Ref''	Dr. Wong, Marriage Counselor	AKA Hostile Hostages
''Men of War (film)|Men of War''	Po		-	rowspan=2|1995	''Kalamazoo''	Justin		-	''Father of the Bride Part II''	Howard Weinstein		-	rowspan=2|1996	''Executive Decision''	Sergeant Louie		-	''Joe's Apartment''	Cockroach	Voice acting|Voice
1997	''Seven Years in Tibet (1997 film)|Seven Years in Tibet''	Ngawang Jigme
rowspan=2|1998	''Slappy and the Stinkers''	Morgan Brinway
''Mulan (1998 film)''	Shang	Voice
2002	''The Salton Sea''	Bubba		-	2004	''Mulan II''	Shang	Straight-to-video Voice
2005	''Stay (film)|Stay''	Dr. Ren		-	2006	''Ira & Abby''	Party Guest

Television

Year	Film	Role	Notes
1983	''No Big Deal''	Miss Karnisian's Class	TV film as Bradd Wong
1986	''Simon & Simon''	Counterboy - Photo Shop Clerk	Episode: "Mobile Home of the Brave"
1987	''Double Switch''	Waiter	TV film
1988	''Crash Course''	Kichi	TV film as Bradd Wong aka ''Driving Academy''
1990	''Goodnight Sweet Wife: A Murder in Boston''	Kim Tan	TV Film aka ''The Charles Stuart Story''
1991	''Alive from Off Center''	Actor	Episode: "Dances in Exile"
1993	''And the Band Played On (film)|And the Band Played On''	Kico Govantes	HBO TV film
1994-95	''All American Girl (1994 TV series)|All-American Girl''	Dr. Stuart Kim	18 episodes
1994	''ABC Afterschool Specials''	Johnny Angel	Episode: "Magical Make-Over"
rowspan=3|1995	''Dazzle''	Teng	TV film
''Happily Ever After: Fairy Tales for Every Child''	Big Bad Wolf|The Wolf	Episode: "Little Red Riding Hood"
''Bless This House''	Johnny Chen	Episode: "Neither a Borrower Nor a Landlord Be"
rowspan=2|1996	''The X-Files''	Det. Glen Chao	Episode: "Hell Money"
''Lauren Hutton and...''	Himself	Episode: "B.D. Wong"
1997-03	''Oz (TV series)|Oz''	Father Ray Mukada	47 episodes
rowspan=3|1998	''The Substitute 2: School's Out''	Warren Drummond	TV film
''Reflections on Ice: Michelle Kwan Skates to the Music of Disney's 'Mulan	Captain Li Shang	TV film
''The Rosie O'Donnell Show''	Himself	Episode: "Episode dated 28 May 1998"
1999	''Chicago Hope''	Dr. Kai Chang	Episode: "List_of_Chicago_Hope_episodes#Season_six_.281999-2000.29|Upstairs, Downstairs"
2000	''Welcome to New York''	Dennis	Episode: "Jim Gets a Wig"
2002	''Kim Possible''	Agent Will Du	Voice Episode: "List_of_Kim_Possible_episodes#Season_1:_2002-2003|Number One"
2001???Present	''Law and Order: Special Victims Unit''	George Huang (Law & Order)|Dr. George Huang	187 episodes
2004	''Century City (television)|Century City''	U.S. Attorney Matthew Chin	Episode: "Pilot"
2007	''Marco Polo (TV film)|Marco Polo''	Pedro	TV film

Video games

Year	Film	Role	Notes
2005	''Kingdom Hearts II''	Captain Li Shang	(English)
2007	''Kingdom_Hearts_II:_Final_Mix%2B#Final_Mix|Kingdom Hearts II: Final Mix+''	Captain Li Shang	(English)

• 1988 Clarence Derwent Award for Most Promising Male ??? M. Butterfly

• 1988 Drama Desk Award for Outstanding Featured Actor in a Play ??? M. Butterfly

• 1988 Theatre World Award ??? M. Butterfly

• 1988 Tony Award for Best Performance by a Featured Actor in a Play ??? M. Butterfly

• 2003 GLAAD Davidson/Valentini Award